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Defending champions Manchester City, Liverpool and QPR are all in action today, while there are several interesting clashes set for Sunday.
Manchester City will take on Fulham at home and they are looking to cut Manchester United lead at the top EPL standings to four points with a win, with United not in action until Sunday against Tottenham.
Liverpool will take on Norwich City, Wigan and Sunderland are against each other, while QPR and there new striker Loic Remy, who is already on the score sheet will take on West Ham United.
Meanwhile, here are the following starting line-ups for the games already on today.
Interestingly, Mario Balotelli, who has been linked with a move to AC Milan is on the bench, so too is striker Sergio Aguero, who has recovered from a hamstring injury.
Carlos Tevez and Edin Dzeko start in the forward line.
Daniel Sturridge gets a starting place for Liverpool.
Manchester City v Fulham
Man City: Hart, Zabaleta, Kompany, Nastasic, Clichy, Barry, Javi Garcia, Milner, Tevez, Silva, Dzeko.
Subs: Pantilimon, Lescott, Nasri, Kolarov, Aguero, Rodwell, Balotelli.
Fulham: Schwarzer, Riether, Hughes, Hangeland, Richardson, Duff, Karagounis, Sidwell, Dejagah, Ruiz, Berbatov. Subs: Etheridge, Senderos, Baird, Petric, Briggs, Rodallega, Kacaniklic.
Liverpool v Norwich
Liverpool: Jones, Wisdom, Carragher, Agger, Johnson, Gerrard, Lucas, Henderson, Suarez, Sturridge, Downing. Subs: Gulacsi, Allen, Borini, Sterling, Shelvey, Skrtel, Robinson.
Norwich: Bunn, Martin, Ryan Bennett, Turner, Garrido, Elliott Bennett, Johnson, Howson, Snodgrass, Tettey, Holt. Subs: Rudd, Jackson, Pilkington, Hoolahan, Barnett, Tierney, Kane.
Referee: Michael Oliver (Northumberland)
West Ham v QPR
West Ham: Jaaskelainen, Demel, Tomkins, Reid, O’Brien, Noble, Diame, Joe Cole, Nolan, Jarvis, Chamakh. Subs: Spiegel, Carlton Cole, Collison, Vaz Te, Taylor, Diarra, Potts.
QPR: Julio Cesar, Onuoha, Nelsen, Hill, Da Silva, Derry, Mbia, Mackie, Taarabt, Wright-Phillips, Remy. Subs: Green, Traore, Ferdinand, Park, Hoilett, Faurlin, Bothroyd.
Referee: Howard Webb (S Yorkshire)
Referee: Jon Moss (W Yorkshire)
Swansea v Stoke
Swansea: Vorm, Rangel, Monk, Williams, Davies, Hernandez, de Guzman, Ki, Michu, Routledge, Shechter. Subs: Tremmel, Bartley, Britton, Graham, Dyer, Lamah, Tiendalli.
Stoke: Begovic, Whitehead, Huth, Shawcross, Cameron, Etherington, Whelan, Nzonzi, Adam, Walters, Crouch. Subs: Sorensen, Palacios, Jones, Owen, Upson, Kightly, Jerome.
Referee: Mike Dean (Wirral)
Wigan v Sunderland
Wigan: Al Habsi, Boyce, Caldwell, Figueroa, Stam, McCarthy, McArthur, Beausejour, Gomez, Di Santo, Maloney. Subs: Robles, Jones, Henriquez, McManaman, Espinoza, Boselli, Golobart.
Sunderland: Mignolet, Gardner, O’Shea, Bramble, Colback, Larsson, N’Diaye, Vaughan, Johnson, Fletcher, Sessegnon. Subs: Westwood, Bardsley, Wickham, McFadden, Kilgallon, McClean, Elmohamady.
Referee: Anthony Taylor (Cheshire)
Newcastle v Reading
Newcastle: Krul, Coloccini, Santon, Debuchy, Williamson, Cabaye, Anita, Cisse, Marveaux, Gutierrez, Shola Ameobi. Subs: Elliot, Perch, Steven Taylor, Bigirimana, Obertan, Sammy Ameobi, Ranger.
Reading: Federici, Pearce, Mariappa, Harte, Kelly, Leigertwood, McCleary, Kebe, McAnuff, Guthrie, Pogrebnyak. Subs: Taylor, Gunter, Morrison, Akpan, Karacan, Le Fondre, Hunt.
Referee: Andre Marriner (W Midlands)